Screening of wood damaging fungi and macrofungi for inhibitors of pancreatic lipase | Zendy

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Screening of wood damaging fungi and macrofungi for inhibitors of pancreatic lipase

Author(s) -

Slanc Petra,

Doljak Bojan,

Mlinarič Aleš,

Štrukelj Borut

Publication year - 2004

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1548

Subject(s) - lipase , pancreatic lipase , dichloromethane , chromogenic , biology , triacylglycerol lipase , methanol , botany , traditional medicine , chemistry , microbiology and biotechnology , food science , enzyme , biochemistry , chromatography , medicine , organic chemistry , solvent

A total of 120 methanol and dichloromethane extracts, from 60 species of wood‐damaging fungi and 50 methanol/water extracts from macrofungi were screened for inhibition of pancreatic lipase using the chromogenic substrate p ‐nitrophenylpalmitate. Of the extracts screened, those from Laetiporus sulphureus , Tylopilus felleus and Hygrocybe conica exhibited the highest lipase inhibitory activities of 83% ± 5%, 96% ± 3% and 97% ± 5%, respectively. Copyright © 2004 John Wiley & Sons, Ltd.

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