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Antioxidant and cytotoxic activities of Retama raetam subsp. Gussonei
Author(s) -
Conforti F.,
Statti G.,
Tundis R.,
Loizzo M. R.,
Bonesi M.,
Menichini F.,
Houghton P. J.
Publication year - 2004
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1496
Subject(s) - antioxidant , dpph , lipid peroxidation , cytotoxic t cell , traditional medicine , pharmacognosy , in vitro , chemistry , biology , botany , biochemistry , biological activity , medicine
Abstract The aim of this study was to evaluate the in vitro antioxidant and cytotoxic activities of the methanol extracts of Retama raetam subsp. gussonei leaves and seeds. The antioxidant activity of the extracts was assessed by means of two different tests: (1) bleaching of the stable 2,2‐diphenyl‐1‐picrylhydrazil (DPPH) radical; and (2) lipid peroxidation of liposomes which were prepared from bovine brain extract. In both tests used leaves extract showed a signicant antioxidant effect. The extract of leaves also demonstrated a good cytotoxic activity against COR‐L23 (large cell carcinoma) cell line. Copyright © 2004 John Wiley & Sons, Ltd.