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Antioxidant and free radical scavenging activities of 5,7,3′‐trihydroxy‐3,6,4′‐trimethoxyflavone from Brickellia veronicaefolia
Author(s) -
Pérez G. R. M.,
Vargas S. R.,
Martinez M. F. J.,
Cordova R. I.
Publication year - 2004
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1445
Subject(s) - antioxidant , scavenging , traditional medicine , chemistry , pharmacognosy , medicine , biochemistry , biological activity , in vitro
The antioxidant and antiradical activities of 5,7,3′‐trihydroxy‐3,6,4′‐trimethoxyavone or centaureidin isolated and characterized from Brickellia veronicaefolia were elucidated by heat‐induced oxidation in a β ‐carotene and linoleic acid system and by the 1,1‐diphenyl‐2‐picrylhydrazyl decoloration test. The centaureidin (32.1%) exhibited antioxidative activity less than that of BHT (95.5%) and α ‐tocopherol (95.9%) on oxidation in a β ‐carotene and linoleic acid system. A moderate antiradical effect (47.6%) compared with BHT (96.7%) and α ‐tocopherol (94.6%) in DPPH decoloration test was found. Copyright © 2004 John Wiley & Sons, Ltd.