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In vitro snake venom detoxifying action of some marine algae of Gulf of Mannar, south‐east coast of India
Author(s) -
Vasanthi Hannah R.,
Jaswanth A.,
Krishnaraj V.,
Rajamanickam G. V.,
Saraswathy A.
Publication year - 2003
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1342
Subject(s) - venom , algae , snake venom , in vitro , biology , pharmacognosy , traditional medicine , pharmacology , toxicology , botany , biological activity , medicine , fishery , biochemistry
Abstract The extract of the brown seaweed Padina boergesenii and the red seaweed Hypnea valentiae was found to detoxify ( in vitro ) the venom of Naja nigricollis . There was a remarkable reduction in the mortality of albino mice after intraperitoneal (i.p.) administration of reconstituted venom with the extract compared to those challenged with the venom only. The survival of the animals exposed to the venom incubated with the different concentrations of the extract was used as the in vitro detoxication parameter. Copyright © 2003 John Wiley & Sons, Ltd.