Antitussive potential of methanol extract of stem bark of  Ficus racemosa  Linn. | Zendy

Bhaskara Rao R. | Zendy; Murugesan T. | Zendy; Pal M. | Zendy; Saha B. P. | Zendy; Mandal S. C. | Zendy

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Antitussive potential of methanol extract of stem bark of Ficus racemosa Linn.

Author(s) -

Bhaskara Rao R.,

Murugesan T.,

Pal M.,

Saha B. P.,

Mandal S. C.

Publication year - 2003

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1325

Subject(s) - traditional medicine , moraceae , bark (sound) , pharmacognosy , methanol , ficus , chemistry , pharmacology , medicine , biological activity , botany , biology , in vitro , biochemistry , ecology , organic chemistry

The methanol extract of Ficus racemosa Linn (Moraceae) (stem bark) (MEFR) was tested for its antitussive potential against a cough induced model by sulphur dioxide gas in mice. The extract demonstrated signicant ( p < 0.001) antitussive activity at all tested dose levels when compared with the control. The antitussive activity of the extract was comparable to that of codeine phosphate (10 mg), a standard antitussive agent. The extract exhibited maximum inhibition of 56.9% at a dose of 200 mg/kg (p.o.) 90 min after administration. Copyright © 2003 John Wiley & Sons, Ltd.

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