Premium
Antifertility effects of Ricinus communis (Linn) on rats
Author(s) -
Sandhyakumary K.,
Bobby R. G.,
Indira M.
Publication year - 2003
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1308
Subject(s) - ricinus , biology , fructose , testosterone (patch) , ethanol , sperm , motility , endocrinology , andrology , medicine , pharmacology , botany , biochemistry , genetics
The antifertility effects of 50% ethanol extracts of Ricinus communis have been studied in male rats. There was a drastic reduction in the epididymal sperm counts. Alteration in the motility, mode of movement and morphology of the sperms were observed. Reductions in the fructose and testosterone levels were suggestive of reduced reproductive performance. Reversibility tests showed that the antifertility effect of Ricinus communis was completely reversible on withdrawal of the drug. The ethanol extracts of Ricinus communis did not cause any hepatotoxicity since the hepatic GOT and GPT levels were unaltered. Copyright © 2003 John Wiley & Sons, Ltd.