Hepatoprotective effect of New Livﬁt®, a polyherbal formulation, is mediated through its free radical scavenging activity | Zendy

Gupta Y. K. | Zendy; Sharma Monisha | Zendy; Chaudhary Geeta | Zendy; Katiyar C. K. | Zendy

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Hepatoprotective effect of New Livﬁt®, a polyherbal formulation, is mediated through its free radical scavenging activity

Author(s) -

Gupta Y. K.,

Sharma Monisha,

Chaudhary Geeta,

Katiyar C. K.

Publication year - 2004

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1272

Subject(s) - pyrogallol , lipid peroxidation , chemistry , pharmacology , oral administration , liver toxicity , traditional medicine , pharmacognosy , toxicity , antioxidant , scavenging , biochemistry , medicine , biological activity , in vitro , organic chemistry

The effect of New Livt®, a polyherbal formulation, was studied on pyrogallol‐induced hepatotoxicity in rats. Administration of pyrogallol 100 mg/kg, i.p. caused a signicant increase in liver enzymes as well as a signicant increase in lipid peroxidation. Simultaneous administration of oral New Livt® and pyrogallol prevented these changes in hepatic damage. The results of the study showed that New Livt® exerted a hepatoprotective effect against pyrogallol induced liver toxicity, which was mediated through its free radical scavenging property. Copyright © 2004 John Wiley & Sons, Ltd.

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