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Evaluation of diuretic activity of the constituents of Clematis montevidensis Spreng. (Ranunculaceae) in rats
Author(s) -
Álvarez M. E.,
María A. O. M.,
Villegas O.,
Saad J. R.
Publication year - 2003
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1268
Subject(s) - ranunculaceae , clematis , diuretic , oleanolic acid , biology , botany , traditional medicine , pharmacology , medicine , herb , alternative medicine , pathology , medicinal herbs
The effects of Clematis montevidensis Spreng. (Ranunculaceae) on urinary excretion of water, sodium and potassium were investigated in rats loaded with isotonic saline solution. The data reported in the present work indicate that the infusions of the root and aerial part of Clematis montevidensis showed a moderate diuretic activity. This effect could be due, at least in part, to the presence of oleanolic acid isolated from this plant. Copyright © 2003 John Wiley & Sons, Ltd.