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Geraniol, the putative anthelmintic principle of Cymbopogon martinii
Author(s) -
Kumaran Asha M.,
D'Souza Prashanth,
Agarwal Amit,
Bokkolla Rama Mohan,
Balasubramaniam Murali
Publication year - 2003
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1267
Subject(s) - geraniol , anthelmintic , linalool , biology , caenorhabditis elegans , nematode , traditional medicine , ed50 , pharmacology , essential oil , botany , in vitro , medicine , biochemistry , ecology , gene
The essential oil of Cymbopogon martinii (palmrosa) and one of its main constituents geraniol were tested for anthelmintic activity ( in vitro ) employing the nematode, Caenorhabditis elegans . Both the substances showed potent anthelmintic activity. The ED 50 of geraniol was found to be 66.7 mcg/mL, suggesting geraniol as the putative anthelmintic principle of palmrosa oil. Copyright © 2003 John Wiley & Sons, Ltd.