Evaluation of antitussive potential of  Ionidium suffruticosam  Ging. (Violaceae) extract in albino mice | Zendy

Boominathan R. | Zendy; Parimala Devi B. | Zendy; Mandal Subhash C. | Zendy

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Evaluation of antitussive potential of Ionidium suffruticosam Ging. (Violaceae) extract in albino mice

Author(s) -

Boominathan R.,

Parimala Devi B.,

Mandal Subhash C.

Publication year - 2003

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1257

Subject(s) - violaceae , traditional medicine , pharmacology , codeine , chemistry , medicine , biology , botany , morphine

The present study was carried out to evaluate the antitussive potential of methanol extract of Ionidium suffruticosam Ging. (Violaceae) which was investigated for its effect on a cough model induced by sulfur dioxide gas in albino mice. It exhibited signi.cant dose‐dependent antitussive activity when compared with the control, 250 and 500 mg/kg (p.o.) of the extract showing 28.37% and 54.16% inhibition of the cough with respect to control group. The antitussive activity of the extract was comparable to that of codeine phosphate, a prototype antitussive agent. Copyright © 2003 John Wiley & Sons, Ltd.

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