Premium
Evaluation of antitussive potential of Ionidium suffruticosam Ging. (Violaceae) extract in albino mice
Author(s) -
Boominathan R.,
Parimala Devi B.,
Mandal Subhash C.
Publication year - 2003
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1257
Subject(s) - violaceae , traditional medicine , pharmacology , codeine , chemistry , medicine , biology , botany , morphine
The present study was carried out to evaluate the antitussive potential of methanol extract of Ionidium suffruticosam Ging. (Violaceae) which was investigated for its effect on a cough model induced by sulfur dioxide gas in albino mice. It exhibited signi.cant dose‐dependent antitussive activity when compared with the control, 250 and 500 mg/kg (p.o.) of the extract showing 28.37% and 54.16% inhibition of the cough with respect to control group. The antitussive activity of the extract was comparable to that of codeine phosphate, a prototype antitussive agent. Copyright © 2003 John Wiley & Sons, Ltd.