Effects of  Rhus coriaria  L. (Anacardiaceae) on lipid peroxidation and free radical scavenging activity | Zendy

Candan Ferda | Zendy; Sökmen Atalay | Zendy

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Effects of Rhus coriaria L. (Anacardiaceae) on lipid peroxidation and free radical scavenging activity

Author(s) -

Candan Ferda,

Sökmen Atalay

Publication year - 2004

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1228

Subject(s) - lipid peroxidation , antioxidant , anacardiaceae , xanthine oxidase , chemistry , pharmacognosy , deoxyribose , radical , biochemistry , traditional medicine , biological activity , botany , biology , in vitro , enzyme , medicine , dna

In order to evaluate the antioxidant potential of Rhus coriaria L. (Anacardiaceae), a well‐known spice, the methanolic extract (water‐soluble part) was prepared and investigated using free radical‐generating systems in vitro . The IC 50 value of the extract for lipid peroxidation was estimated as 1200 µg/mL in the Fe +2 ‐ascorbate system while those for superoxide‐scavenging activity in the xanthine‐xanthine oxidase method and hydroxyl radical scavenging activity in the deoxyribose decomposition method were 282.92 µg/mL and 3850 µg/mL, respectively. These data suggest that the methanolic extracts of Rhus coriaria L. fruits have considerable antioxidant activity against free radicals and lipid peroxidation in vitro , a fact that may encourage in vivo studies. Copyright © 2004 John Wiley & Sons, Ltd.

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