Analgesic and anti‐inﬂammatory activity of the leaf essential oil of  Laurus nobilis  Linn. | Zendy

Sayyah M. | Zendy; Saroukhani G. | Zendy; Peirovi A. | Zendy; Kamalinejad M. | Zendy

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Analgesic and anti‐inﬂammatory activity of the leaf essential oil of Laurus nobilis Linn.

Author(s) -

Sayyah M.,

Saroukhani G.,

Peirovi A.,

Kamalinejad M.

Publication year - 2003

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1197

Subject(s) - laurus nobilis , analgesic , lauraceae , essential oil , traditional medicine , anti inflammatory , medicine , pharmacology , muscle relaxant , sedative , piroxicam , nociception , pharmacognosy , morphine , chemistry , biological activity , biology , botany , food science , biochemistry , alternative medicine , pathology , in vitro , receptor

The leaf essential oil of Laurus nobilis Linn. (Lauraceae) has been evaluated for antinociceptive and anti‐inammatory activities in mice and rats. The essential oil exhibited: (1) a signicant analgesic effect in tail‐ick and formalin tests; (2) a dose‐dependent anti‐inammatory effect in the formalin‐induced edema and (3) a moderate sedative effect at the anti‐inammatory doses. The analgesic and anti‐inammatory effect of the essential oil was comparable to reference analgesics and non‐steroid anti‐inammatory drugs: morphine and piroxicam. Present results make the essential oil worthy of further investigations. Copyright © 2003 John Wiley & Sons, Ltd.

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