Enzyme inhibition by the molluscicidal agent  Punica granatum  Linn. bark and   Canna indica  Linn. root | Zendy

Tripathi Sanjay M. | Zendy; Singh V. K. | Zendy; Singh Sanjay | Zendy; Singh D. K. | Zendy

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Enzyme inhibition by the molluscicidal agent Punica granatum Linn. bark and Canna indica Linn. root

Author(s) -

Tripathi Sanjay M.,

Singh V. K.,

Singh Sanjay,

Singh D. K.

Publication year - 2004

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1168

Subject(s) - bark (sound) , alkaline phosphatase , enzyme , biology , traditional medicine , in vivo , punica , molluscicide , acetylcholinesterase , botany , biochemistry , chemistry , horticulture , snail , medicine , ecology , microbiology and biotechnology

Sublethal in vivo 24 h exposure to (40% and 80% of 24 h LC 50 ) active fractions of Punica granatum bark or Canna indica root or in combination with other plant‐derived molluscicides signicantly inhibited the activity of acetylcholinesterase, acid/alkaline phosphatase, Na + K + ATPase and lactic dehydrogenase in the nervous tissue of Lymnaea acuminata . The inhibition kinetics of these enzymes indicates that active fractions of both the plants caused a competitive inhibition of AChE, LDH, ALP, ACP and Na + K + ATPase. Copyright © 2004 John Wiley & Sons, Ltd.

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