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Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats
Author(s) -
Stanely Mainzen Prince P.,
Me Venugopal P.
Publication year - 2003
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1130
Subject(s) - tinospora cordifolia , traditional medicine , diabetes mellitus , medicine , alcohol , phytotherapy , alloxan , pharmacognosy , oral administration , pharmacology , urine , chemistry , endocrinology , biochemistry , biological activity , alternative medicine , pathology , in vitro
The present investigation was undertaken to evaluate the hypoglycaemic and hypolipidaemic effects of an alcohol extract of Tinospora cordifolia roots, an indigenous plant used in Ayurvedic medicine in India. Oral administration of the extract of Tinospora cordifolia (TCREt) roots for 6 weeks resulted in a signicant reduction in blood and urine glucose and in lipids in serum and tissues in alloxan diabetic rats. The extract also prevented a decrease in body weight. Thus our study clearly shows that an alcohol TCREt has a hypoglycaemic and hypolipidaemic action. Copyright © 2003 John Wiley & Sons, Ltd.