Correction of the high blood viscosity syndrome by a mixture of diquertin and ascorbic acid  in vitro  and  in vivo | Zendy

Plotnikov M. B. | Zendy; Aliev O. I. | Zendy; Maslov M. Ju. | Zendy; Vasiliev A. S. | Zendy; Tjukavki. A. | Zendy

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Correction of the high blood viscosity syndrome by a mixture of diquertin and ascorbic acid in vitro and in vivo

Author(s) -

Plotnikov M. B.,

Aliev O. I.,

Maslov M. Ju.,

Vasiliev A. S.,

Tjukavki. A.

Publication year - 2003

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1113

Subject(s) - ascorbic acid , blood viscosity , in vivo , viscosity , rheology , chemistry , pharmacology , medicine , food science , materials science , biology , microbiology and biotechnology , composite material

Diquertin was shown to diminish blood viscosity, to decrease the aggregation of erythrocytes, and to increase their deformability using a model of the high blood viscosity syndrome in vitro . A mixture of Diquertin with Ascorbic Acid was more effective in improving rheological indicators of blood, then either Diquertin or Tanakan. On a model of chronic brain ischemia, which is accompanied by signicant deterioration of the rheological properties of blood, it was shown that a therapy with a mixture of Diquertin and Ascorbic Acid decreases the expression of the high blood viscosity syndrome. Copyright © 2003 John Wiley & Sons, Ltd.

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