Correction of haemorheological disturbances in myocardial infarction by diquertin and ascorbic acid | Zendy

Plotnikov M. B. | Zendy; Aliev O. I. | Zendy; Maslov M. Ju | Zendy; Vasiliev A. S. | Zendy; Tjukavki. A. | Zendy

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Correction of haemorheological disturbances in myocardial infarction by diquertin and ascorbic acid

Author(s) -

Plotnikov M. B.,

Aliev O. I.,

Maslov M. Ju,

Vasiliev A. S.,

Tjukavki. A.

Publication year - 2003

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1082

Subject(s) - ascorbic acid , blood viscosity , fibrinogen , plasma viscosity , myocardial infarction , erythrocyte deformability , hemorheology , medicine , whole blood , viscosity , chemistry , cardiology , red blood cell , biochemistry , food science , materials science , composite material

In a model of the high blood viscosity syndrome, developed after myocardial infarction in rats, it was observed that a therapy of a combination of diquertin (20 mg/kg) and ascorbic acid (50 mg/kg) for a period of 6 days, resulted in an improvement of haemorheological indices. The decrease in blood viscosity was primarily due to an improved deformability of erythrocytes, and to some extent, due to a decrease in the content of plasma fibrinogen and erythrocyte aggregation. Copyright © 2003 John Wiley & Sons, Ltd.

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