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Potential antiamoebic property of the roots of Piper longum Linn.
Author(s) -
Ghoshal Sheela,
Lakshmi V.
Publication year - 2002
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1014
Subject(s) - piper , amoebiasis , traditional medicine , piperaceae , biology , medicine , microbiology and biotechnology
In an earlier study we reported the effect of ethanol extracts of Piper longum fruit against caecal amoebiasis in rats. A follow‐up study to determine whether the roots possess similar antiamoebic activity was carried out. The ethanolic extract of roots was amoebicidal at 1000 μg/mL in vitro and cured 88% of caecal amoebiasis cases, suggesting that both the root and fruit of P. longum possess antiamoebic activity to approximately the same extent. Copyright © 2002 John Wiley & Sons, Ltd.