Evaluation of antipyretic potential of  Leucas lavandulaefolia  (Labiatae) aerial part extract | Zendy

Mukherjee Kakali | Zendy; Saha B. P. | Zendy; Mukherjee Pulok K. | Zendy

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Evaluation of antipyretic potential of Leucas lavandulaefolia (Labiatae) aerial part extract

Author(s) -

Mukherjee Kakali,

Saha B. P.,

Mukherjee Pulok K.

Publication year - 2002

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1013

Subject(s) - antipyretic , traditional medicine , rectal temperature , leucas , medicine , yeast , pharmacognosy , phytotherapy , analgesic , pharmacology , chemistry , biology , biological activity , anesthesia , in vitro , biochemistry , alternative medicine , pathology , fishery

Methanol extract of Leucas lavandulaefolia (LLFE) was subjected to antipyretic evaluation with yeast‐induced pyrexia in rats. A yeast suspension (10 mL/kg, s.c.) increased the rectal temperature 19 h after administration. The extract at doses of 100, 200, 400 mg/kg (i.p.) produced significant dose dependent lowering of body temperature in yeast‐provoked elevation of body temperature in rats. The antipyretic effect produced was comparable to that of a standard antipyretic drug, paracetamol. Copyright © 2002 John Wiley & Sons, Ltd.

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