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Flavonoids—a new direction for the treatment of fluid retention?
Author(s) -
Christie Samantha,
Walker Ann F.,
Lewith George T.
Publication year - 2001
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.1011
Subject(s) - flavonoid , medicine , pathophysiology , intensive care medicine , pathology , biology , biochemistry , antioxidant
Flavonoid extracts are important for the health of the micro‐blood vessel network and are clinically exploited in this way by medical herbalists and physicians in mainland Europe. In the present review, we provide preliminary evidence that suggests that plant flavonoid extracts from dietary sources facilitate the repair of vessel damage responsible for ‘small blood vessel permeability’. Correction of this pathophysiological abnormality is known to lead to a reduction in symptoms of diffuse benign fluid retention including swollen limbs, fingers, breasts and the tissue surrounding the eye area. There is currently little orthodox treatment for this type of fluid retention except diuretics which are not without side effects and fail to address the underlying cause of the disorder. This paper marshals available data including some preliminary studies that suggest that detailed scientific study of this clinical area and its treatment through flavonoid intervention is warranted. Copyright © 2001 John Wiley & Sons, Ltd.