Antitubercular constituents from the hexane fraction of  Morinda citrifolia  Linn. (Rubiaceae) | Zendy

Saludes Jonel P. | Zendy; Garson Mary J. | Zendy; Franzblau Scott G. | Zendy; Aguinaldo Alicia M. | Zendy

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Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae)

Author(s) -

Saludes Jonel P.,

Garson Mary J.,

Franzblau Scott G.,

Aguinaldo Alicia M.

Publication year - 2002

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.1003

Subject(s) - phytol , rubiaceae , cycloartenol , morinda , stigmasterol , fraction (chemistry) , hexane , traditional medicine , chemistry , chromatography , sterol , botany , biology , medicine , biochemistry , cholesterol

A crude ethanol extract and hexane fraction from Morinda citrifolia Linn. (Rubiaceae) show antitubercular activity. The major constituents of the hexane fraction are E ‐phytol, cycloartenol, stigmasterol, β‐sitosterol, campesta‐5,7,22‐trien‐3β‐ol and the ketosteroids stigmasta‐4‐en‐3‐one and stigmasta‐4‐22‐dien‐3‐one. E ‐Phytol, a mixture of the two ketosteroids, and the epidioxysterol derived from campesta‐5,7,22‐trien‐3β‐ol all show pronounced antitubercular activity. Copyright © 2002 John Wiley & Sons, Ltd.

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