Sample size calculation for the one‐sample log‐rank test | Zendy

Wu Jianrong | Zendy

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Sample size calculation for the one‐sample log‐rank test

Author(s) -

Wu Jianrong

Publication year - 2014

Publication title -

pharmaceutical statistics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.421

H-Index - 38

eISSN - 1539-1612

pISSN - 1539-1604

DOI - 10.1002/pst.1654

Subject(s) - sample size determination , statistics , mathematics , log rank test , statistic , sample (material) , rank (graph theory) , variance (accounting) , one way analysis of variance , population , analysis of variance , test statistic , statistical hypothesis testing , survival analysis , combinatorics , medicine , chemistry , accounting , chromatography , business , environmental health

In this paper, an exact variance of the one‐sample log‐rank test statistic is derived under the alternative hypothesis, and a sample size formula is proposed based on the derived exact variance. Simulation results showed that the proposed sample size formula provides adequate power to design a study to compare the survival of a single sample with that of a standard population. Copyright © 2014 John Wiley & Sons, Ltd.

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