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Reproducibility of clinical data II: categorical outcomes
Author(s) -
Blackman Nicole JillMarie
Publication year - 2004
Publication title -
pharmaceutical statistics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.421
H-Index - 38
eISSN - 1539-1612
pISSN - 1539-1604
DOI - 10.1002/pst.105
Subject(s) - reproducibility , categorical variable , intraclass correlation , variance (accounting) , statistics , context (archaeology) , relevance (law) , computer science , econometrics , ordinal data , data mining , mathematics , geography , accounting , archaeology , political science , law , business
In this second part of this paper, reproducibility of discrete ordinal and nominal outcomes is addressed. The first part deals with continuous outcomes, concentrating on intraclass correlation ( ρ ) in the context of one‐way analysis of variance. For categorical data, the focus has generally not been on a meaningful population parameter such as ρ . However, intraclass correlation has been defined for discrete ordinal data, ρ c , and for nominal data, κ I . Therefore, a unified approach to reproducibility is proposed. The relevance of these parameters is outlined. Estimation and inferential procedures for ρ c and κ I are reviewed, together with worked examples. Topics related to reproducibility that are not addressed in either this or the previous paper are highlighted. Considerations for designing reproducibility studies and for interpreting their results are provided. Copyright © 2004 John Wiley & Sons, Ltd.