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Voltammetric determination of erythromycin in water samples using a boron‐doped diamond electrode
Author(s) -
Radičová Monika,
Behúl Miroslav,
Vojs Marian,
Bodor Róbert,
Vojs Staňová Andrea
Publication year - 2015
Publication title -
physica status solidi (b)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.51
H-Index - 109
eISSN - 1521-3951
pISSN - 0370-1972
DOI - 10.1002/pssb.201552245
Subject(s) - repeatability , electrode , analytical chemistry (journal) , erythromycin , boron , ammonium acetate , calibration curve , diamond , detection limit , square wave , chemistry , voltammetry , buffer solution , materials science , electrochemistry , chromatography , voltage , high performance liquid chromatography , biochemistry , physics , organic chemistry , quantum mechanics , antibiotics
A new, simple, sensitive, and low‐cost voltammetric method using an as‐grown boron‐doped diamond electrode was developed for the determination of erythromycin in environmental (water) samples. Erythromycin provided an irreversible oxidation peak at a potential of + 0.87 V versus Ag/AgCl/KCl (3 mol/L) electrode in an ammonium acetate buffer (pH 5). Under optimal experimental conditions, square‐wave voltammetry was used for the determination of erythromycin. The calibration curves showed good linearity in a concentration range from 6.8 to 68.1 μmol/L with the coefficient of determination R 2 = 0.9993. The limit of detection of the proposed method was 1.1 μmol/L. Very good repeatability ( n = 7) at three different concentration levels (6.8, 13.6 and 20.4 μmol/L) was obtained (RSD of 2.4, 1.8, 1.6, respectively). The developed square‐wave method was successfully applied to the determination of erythromycin in several different water samples with good recovery (from 89 to 107%).