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Force spectroscopy measurements of MoSIx nanowires with functionalized molecules
Author(s) -
Ploscaru M.,
Kokalj Sasa Jenko,
Uplaznik M.,
Vengust D.,
Turk D.,
Mihailovic D.
Publication year - 2006
Publication title -
physica status solidi (b)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.51
H-Index - 109
eISSN - 1521-3951
pISSN - 0370-1972
DOI - 10.1002/pssb.200669204
Subject(s) - nanowire , force spectroscopy , surface modification , nanotechnology , molecule , materials science , chemistry , atomic force microscopy , chemical engineering , organic chemistry , engineering
We report a simple method of functionalization of MoSIx nanowires with biomaterials via the thiol group. We succeed to immobilize iodinated and sulphated high molecular mass thyroglobulin proteins on MoSIx nanowires. By controlling the preparation of the nanowires before self‐assembly we can attach proteins either at the ends or achieve complete wrapping of the nanowires. The control parameter is the S and I stoichiometry ratio of the MoSIx nanowires. Breaking force measurements were performed in order to confirm and characterise the wrapping of the nanowires with the proteins. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)