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Implantable Neuroamplifers for Electrocorticography Using Flexible and Biocompatible Technology
Author(s) -
Marcoleta Juan Pablo,
Nogueira Waldo,
Yoma Néstor Becerra,
Wuth Jorge,
Jakimovski Filip,
Fuenzalida Victor M.,
Doll Theodor
Publication year - 2020
Publication title -
physica status solidi (a)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 104
eISSN - 1862-6319
pISSN - 1862-6300
DOI - 10.1002/pssa.201900830
Subject(s) - electrocorticography , computer science , amplifier , signal (programming language) , electroencephalography , flexibility (engineering) , electronics , electronic engineering , noise (video) , power (physics) , multiplexing , power consumption , electrical engineering , artificial intelligence , engineering , telecommunications , neuroscience , physics , mathematics , bandwidth (computing) , statistics , quantum mechanics , image (mathematics) , biology , programming language
Brain signals such as electroencephalography (EEG) and electrocorticography (ECoG) are used to diagnose epilepsy. ECoG signals are small and therefore require large amplification while keeping the recording electronics small enough to adapt to the surface of the brain. Moreover, the components have to be of low power to reduce the risk of brain damage while recording the brain. Herein, a neuroamplifier that is integrated in an ECoG is described. The amplifier, in combination with a novel multiplexing system that reduces the number of required amplifiers and ensures the flexibility of the ECoG, achieves the desired signal‐to‐noise ratio while reducing power consumption. The feasibility of the proposed design is validated though electronic simulations for different input signals, analyzing the actual amplification achieved and the response times. Moreover the circuit is implemented and real measurements are provided validating the simulations.