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Multi‐Well Sensor Platform Based on a Partially Etched Structure of a Light‐Addressable Potentiometric Sensor
Author(s) -
Truong Hoang Anh,
Werner Carl Frederik,
Miyamoto Koichiro,
Yoshinobu Tatsuo
Publication year - 2019
Publication title -
physica status solidi (a)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 104
eISSN - 1862-6319
pISSN - 1862-6300
DOI - 10.1002/pssa.201800764
Subject(s) - potentiometric sensor , potentiometric titration , frame rate , signal (programming language) , materials science , optoelectronics , computer science , chemistry , electrode , artificial intelligence , programming language
A multi‐well‐structured light‐addressable potentiometric sensor (LAPS) plate is developed for measuring a plurality of sample solutions on a single sensor plate. It is also capable of high‐resolution chemical imaging inside the well structure. It can be applied, for example, to quantification of metabolic activities and imaging of biological samples incubated in the well structure. A minimum pattern size of 20 µm line is visualized and a wider frequency bandwidth of up to 200 kHz for the sensor signal is obtained in the well structure, which will be suitable for recording chemical images at a high‐frame‐rate.