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Application of Silver Antibacterial and Antifungal Nanolayers for Ocular Prostheses Coating
Author(s) -
Koev Krassimir,
Donkov Nikolai,
Stankova Nadya,
Moraliiski Emil,
Najdenski Hristo,
Nurgaliev Timerfayaz,
Zaharieva Maya,
Avramov Latchezar
Publication year - 2019
Publication title -
physica status solidi (a)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 104
eISSN - 1862-6319
pISSN - 1862-6300
DOI - 10.1002/pssa.201800695
Subject(s) - candida albicans , staphylococcus aureus , microbiology and biotechnology , antifungal , pseudomonas aeruginosa , escherichia coli , materials science , antibacterial activity , corpus albicans , chemistry , bacteria , biology , biochemistry , genetics , gene
The paper reports on antibacterial and antifungal properties of Ag‐doped Al 2 O 3 nanolayers deposited by RF reactive magnetron sputtering on glass ocular prostheses. The study is provoked by the need of suppressing the infections caused by pathogenic microorganisms following the placement of ocular prostheses. This brings about the idea of forming protective coatings with antibacterial and antifungal properties on the prostheses. The surface elemental composition and the morphological characteristics of the coatings are investigated by XPS and SEM measurements. Further, the microbiological studies are conducted to establish the antibacterial and antifungal action of the nanocomposite Ag/Al 2 O 3 layers against Gram‐positive and ‐negative bacteria, and Candida albicans . The strongest action of the layers is found against Pseudomonas aeruginosa − full inactivation after 2 h; Escherichia coli and Candida albicans – full inactivation after 5 h; Staphylococcus aureus − full inactivation after 24 h. The experimental findings suggest a very promising application of such antibacterial and antifungal Ag/Al 2 O 3 nanolayers regarding the reduction of eye infections when implanting ocular prostheses.