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Front Cover: Diamond as a nanomedical agent for versatile applications in drug delivery, imaging, and sensing (Phys. Status Solidi A 9/2012)
Author(s) -
Man Han B.,
Ho Dean
Publication year - 2012
Publication title -
physica status solidi (a)
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.532
H-Index - 104
eISSN - 1862-6319
pISSN - 1862-6300
DOI - 10.1002/pssa.201290022
Subject(s) - drug delivery , nanotechnology , diamond , materials science , nanodiamond , biocompatibility , biomedical engineering , medicine , composite material , metallurgy
The front‐cover image, taken from the article by Han B. Man et al. ( pp. 1811–1818 ), depicts a dual‐layered PEGDA patch embedded with nanodiamond—drug complexes. Nanodiamonds, which have been loaded with the chemotherapeutic Daunorubicin (red), are being eluted from the center of the patch (purple) while mediating sustained delivery of therapeutics with reduced burst release. The outer ring (green) contains another chemotherapeutic, i.e. unmodifi ed Temozolomide. The multi‐layered architecture of this patch is able to facilitate sequential release of both drugs while preserving drug activity. The image also refers to the Feature Article by Han B. Man and Dean Ho ( pp. 1609–1618 ), wherein the properties of nanodiamonds and diamond‐based devices are discussed, with a focus on therapeutic delivery in addition to insight into their use in imaging, devices, implants/coatings, and biocompatibility.