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Chinese hamster ovary cell viability on hydrogen and oxygen terminated nano‐ and microcrystalline diamond surfaces
Author(s) -
Smisdom Nick,
Smets Ilse,
Williams Oliver A.,
Daenen Michaël,
Wenmackers Sylvia,
Haenen Ken,
Nesládek Miloš,
D'Haen Jan,
Wagner Patrick,
Rigo JeanMichel,
Ameloot Marcel,
vandeVen Martin
Publication year - 2009
Publication title -
physica status solidi (a)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 104
eISSN - 1862-6319
pISSN - 1862-6300
DOI - 10.1002/pssa.200982206
Subject(s) - microcrystalline , chinese hamster ovary cell , oxygen , diamond , viability assay , materials science , hydrogen , nano , chemistry , chemical engineering , biophysics , cell , biology , composite material , biochemistry , crystallography , organic chemistry , receptor , engineering
Transfected Chinese hamster ovary cells were cultured on bare uncoated chemical vapor deposited thin nano‐ and microcrystalline diamond surfaces, hydrophobic hydrogen‐ and hydrophilic oxygen‐terminated. Optical and biochemical analyses show that compared to glass controls, growth and viability were not significantly affected (one‐way‐analysis of variance, ANOVA). Based on two‐way ANOVA analyses, neither grain size nor surface termination had a significant influence until 5 days post‐seeding.