Porous silicon versus its composite with C 60 : testing in vitro | Zendy

Kuznetsov S. N. | Zendy; Volkova T. O. | Zendy; Pikulev V. B. | Zendy; Saren A. A. | Zendy; Gardin Yu. E. | Zendy; Gurtov V. A. | Zendy

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Porous silicon versus its composite with C 60 : testing in vitro

Author(s) -

Kuznetsov S. N.,

Volkova T. O.,

Pikulev V. B.,

Saren A. A.,

Gardin Yu. E.,

Gurtov V. A.

Publication year - 2009

Publication title -

physica status solidi (a)

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.532

H-Index - 104

eISSN - 1862-6319

pISSN - 1862-6300

DOI - 10.1002/pssa.200881059

Subject(s) - photosensitizer , composite number , fullerene , photodynamic therapy , porous silicon , silicon , in vitro , porosity , cytotoxicity , materials science , toxicity , chemistry , nanotechnology , nuclear chemistry , photochemistry , optoelectronics , composite material , organic chemistry , biochemistry

We have studied in vitro an efficiency of the promising photosensitizer for photodynamic therapy (PDT) on the base of porous silicon (PSi) impregnated with fullerene C 60 . It is shown that a low concentration addition of fullerene boosts sharply a cancer cell killing in comparison with the pristine PSi. A dark toxicity of the proposed composite drug for PDT does not exceed that for the pristine PSi as it was revealed for observation period of five days. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

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