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Highly sensitive spin‐valve devices for chip‐cytometers
Author(s) -
Roh Jong Wook,
Son OhTaek,
Lee Young Tack,
Lee Kyoungil,
Jung HyoIl,
Lee Wooyoung
Publication year - 2009
Publication title -
physica status solidi (a)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 104
eISSN - 1862-6319
pISSN - 1862-6300
DOI - 10.1002/pssa.200824469
Subject(s) - spin valve , microfluidics , magnetic bead , chip , materials science , microfluidic chip , lab on a chip , optoelectronics , nanotechnology , channel (broadcasting) , magnetic field , chemistry , engineering , electrical engineering , chromatography , physics , magnetization , quantum mechanics
The highly sensitive spin‐valve devices integrated with a microfluidic channel have been studied for cell counting in a chip‐cytometer. The presence or absence of a single magnetic bead was successfully detected by direct measurement of fringe fields emanating from magnetic beads using spin‐valve devices. The real‐time detection was also successfully confirmed by the direct measurement of magnetic fields generated from the magnetic beads passing an active sensing area of a spin‐valve device integrated with a microfluidic channel. Our results show the possibility of implementing a chip‐cytometer for biological applications using the highly sensitive spin‐valve devices integrated with a microfluidic device. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)