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All‐polymer microfluidic particle size sorter for biomedical applications
Author(s) -
Fernandez Javier G.,
Mills Christopher A.,
Rodríguez Romen,
Gomila Gabriel,
Samitier Josep
Publication year - 2006
Publication title -
physica status solidi (a)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 104
eISSN - 1862-6319
pISSN - 1862-6300
DOI - 10.1002/pssa.200566111
Subject(s) - microfluidics , nanotechnology , polymer , materials science , particle size , particle (ecology) , sorting , biocompatible material , transparency (behavior) , computer science , biomedical engineering , chemical engineering , engineering , composite material , computer security , oceanography , programming language , geology
The design and method for the production of an all‐polymer microfluidic particle sorter, for use in biomedical applications, is described. The sorter is made from biocompatible materials with properties, such as high optical transparency, that make it useful in a biological laboratory. The method of sorting is designed to be gentle on biological species, using a method of guiding the particles towards the filter, and has been successfully used to separate latex beads depending on their diameters. Preliminary qualitative experiments have been able to separate beads of 45 and 90 μm in diameter from a mixture of the two. These dimensions are on the same scale as those of some eukaryotic cells. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)