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Lipid and carbohydrate based adjuvant/carriers in immunology
Author(s) -
McGeary Ross P.,
Olive Colleen,
Toth Istvan
Publication year - 2003
Publication title -
journal of peptide science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 66
eISSN - 1099-1387
pISSN - 1075-2617
DOI - 10.1002/psc.467
Subject(s) - adjuvant , vaccine adjuvant , immunology , lipid a , identification (biology) , vaccination , medicine , computational biology , biology , botany , lipopolysaccharide
This review discusses various issues regarding vaccines; what are they and how they work, safety aspects, the role of adjuvants and carriers in vaccination, synthetic peptides as immunogens, and new technologies for vaccine development and delivery including the identification of novel adjuvants for mucosal vaccine delivery. There has been a recent increase of interest in the use of lipids and carbohydrates as adjuvants, and so a particular emphasis is placed on adjuvants derived from lipids or carbohydrates, or from both. Copyright © 2003 European Peptide Society and John Wiley & Sons, Ltd.