Solid‐phase synthesis of C‐terminal azapeptides | Zendy

Doan NgocDuc | Zendy; Zhang Jinqiang | Zendy; Traoré Mariam | Zendy; Kamdem Winnie | Zendy; Lubell William D. | Zendy

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Solid‐phase synthesis of C‐terminal azapeptides

Author(s) -

Doan NgocDuc,

Zhang Jinqiang,

Traoré Mariam,

Kamdem Winnie,

Lubell William D.

Publication year - 2015

Publication title -

journal of peptide science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 66

eISSN - 1099-1387

pISSN - 1075-2617

DOI - 10.1002/psc.2711

Subject(s) - regioselectivity , solid phase synthesis , residue (chemistry) , peptide , alkylation , peptide synthesis , combinatorial chemistry , chemistry , stereochemistry , terminal (telecommunication) , biochemistry , catalysis , computer science , telecommunications

The solid‐phase synthesis of azapeptides possessing a C‐terminal aza‐residue has been accomplished by a protocol featuring regioselective alkylation of benzhydrylidene‐aza‐glycinamide and illustrated by the syntheses of [aza‐Lys 6 ] growth‐hormone‐releasing peptide‐6 analogs. Copyright © 2015 European Peptide Society and John Wiley & Sons, Ltd.

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