Premium
Chemical synthesis of the S‐linked glycopeptide, sublancin
Author(s) -
Katayama Hidekazu,
Asahina Yuya,
Hojo Hironobu
Publication year - 2011
Publication title -
journal of peptide science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 66
eISSN - 1099-1387
pISSN - 1075-2617
DOI - 10.1002/psc.1406
Subject(s) - glycopeptide , bacillus subtilis , disulfide bond , peptide , chemistry , peptide synthesis , combinatorial chemistry , amino acid , stereochemistry , solid phase synthesis , biochemistry , biology , bacteria , antibiotics , genetics
Sublancin is an S‐linked glycopeptide produced by Bacillus subtilis 168 and consists of 37 amino acid residues with two disulfide bonds. In this study, we synthesized sublancin by Fmoc‐based solid‐phase peptide synthesis and chemoselective disulfide formation reactions. Copyright © 2011 European Peptide Society and John Wiley & Sons, Ltd.