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Acidic derivatives of the fungicide fenpiclonil: effect of adding a methyl group to the N ‐substituted chain on systemicity and fungicidal activity
Author(s) -
Chollet JeanFrançois,
Rocher Françoise,
Jousse Cyril,
DelétageGrandon Céline,
Bashiardes Georges,
Bonnemain JeanLouis
Publication year - 2005
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.977
Subject(s) - fungicide , chemistry , pyrrole , fungus , stereochemistry , medicinal chemistry , organic chemistry , biology , botany
A new acidic derivative of the fungicide fenpiclonil was synthesized containing a methyl group on the alpha‐position of the carboxyl function of N ‐carboxymethyl‐3‐cyano‐4‐(2,3‐dichlorophenyl)pyrrole. The phloem mobility of the resulting N ‐(1‐carboxyethyl)‐3‐cyano‐4‐(2,3‐dichlorophenyl)pyrrole was comparable with that of the former compound, but was higher at external pH 5.0. Unlike the derivatives previously synthesized, it was comparable with fenpiclonil in its fungicidal activity against the pathogenic fungus Eutypa lata . Copyright © 2004 Society of Chemical Industry