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Antifungal properties of pristimerin and celastrol isolated from Celastrus hypoleucus
Author(s) -
Luo DuQiang,
Wang Hong,
Tian Xuan,
Shao HongJun,
Liu JiKai
Publication year - 2005
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.953
Subject(s) - celastrol , powdery mildew , glomerella cingulata , antifungal , traditional medicine , rhizoctonia solani , biology , chemistry , botany , colletotrichum gloeosporioides , medicine , microbiology and biotechnology , biochemistry , apoptosis
Pristimerin and celastrol isolated from the roots of Celastrus hypoleucus (Oliv) Warb f argutior Loes exhibited inhibitory effects against diverse phytopathogenic fungi. Pristimerin and celastrol were found to inhibit the mycelial growth of Rhizoctonia solani Kühn and Glomerella cingulata (Stonem) Spauld & Schrenk in vitro by 83.6 and 62.6%, respectively, at 10 µg ml −1 . Pristimerin showed good preventive effect (96.7% at 100 µg ml −1 ) and curative effect (66.5% at 100 µg ml −1 ) against wheat powdery mildew in vivo . For celastrol, the preventive and curative effects against wheat powdery mildew were 80.5 and 45.4%, respectively, at 100 µg ml −1 . Copyright © 2004 Society of Chemical Industry