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EK‐2612, a new cyclohexane‐1,3‐dione possessing selectivity between rice ( Oryza sativa ) and barnyardgrass ( Echinochloa crus‐galli )
Author(s) -
Kim TaeJoon,
Kim JinSeog,
Hong Kyoung Sik,
Hwang InTaek,
Kim Kyoung Mahn,
Kim HyeongRae,
Yun Cho Kwang
Publication year - 2004
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.868
Subject(s) - echinochloa crus galli , oryza sativa , echinochloa , cyclohexane , biology , chemistry , horticulture , weed control , agronomy , organic chemistry , biochemistry , gene
A newly synthesized experimental compound, EK‐2612 is one of the class of cyclohexane‐1,3‐diones which are commonly known to be grasskillers. A greenhouse study was conducted to evaluate the herbicidal performances of EK‐2612 on several grass species in comparison with tralkoxydim, a commercialized cyclohexanedione derivative. Like tralkoxydim, the compound EK‐2612 showed excellent control efficacy on most grass weeds tested through foliar application rates between 250 and 63 g AI ha −1 . Unlike tralkoxydim, however, EK‐2612 showed a good rice safety, and there was no rice damage observed at the level below 125 g AI ha −1 , while rice injury developed at the same application rates of tralkoxydim. With this rice safety, EK‐2612 controlled barnyardgrass effectively up to the two‐leaf stage under both submerged and dried paddy conditions. An in vitro ACCase assay indicated that EK‐2612 is a strong ACCase inhibitor; however, the dose‐response was not substantially different in rice and barnyardgrass, showing I 50 values of 0.1 and 0.12 µ M , respectively. These results suggest that the compound EK‐2612 is targeting plant ACCase, but the whole‐plant rice safety is not attributable to a different inhibition of the target site in rice from that in barnyardgrass. Copyright © 2004 Society of Chemical Industry