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Acaricidal activity of Cnidium officinale rhizome‐derived butylidenephthalide against Tyrophagus putrescentiae (Acari: Acaridae)
Author(s) -
Kwon JiHoon,
Ahn YoungJoon
Publication year - 2003
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.607
Subject(s) - tyrophagus putrescentiae , acaridae , benzyl benzoate , rhizome , deet , fumigation , toxicology , indoxacarb , acari , acaricide , chemistry , food science , botany , biology , acariformes , horticulture , pesticide , organic chemistry , agronomy
The acaricidal activity of materials derived from the rhizome of Cnidium officinale Makino against Tyrophagus putrescentiae Schrank adults was examined using direct contact application and fumigation methods, and compared with that of benzyl benzoate and N,N ‐diethyl‐ m ‐toluamide (DEET). The biologically active constituent of the Cnidium rhizome was identified as butylidenephthalide by spectroscopic analyses. On the basis of 24‐h LD 50 values, acaricidal activity was more pronounced with butylidenephthalide (5.80 µg cm −2 ) than with benzyl benzoate (9.75 µg cm −2 ) and DEET (16.26 µg cm −2 ). In typical poisoning symptoms, butylidenephthalide resulted in lethargy of treated mites, leading to death without knockdown, whereas benzyl benzoate and DEET caused death associated with uncoordinated behaviour. In a fumigation test with T putrescentiae adults, butylidenephthalide was much more effective in closed containers than in open ones, indicating that the effects of this compound were largely due to action in the vapour phase. Naturally occurring C officinale rhizome‐derived materials merit further study as potential T putrescentiae control agents or as lead compounds. © 2002 Society of Chemical Industry