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The stereoisomerism of second generation anticoagulant rodenticides: a way to improve this class of molecules to meet the requirements of society?
Author(s) -
Lattard Virginie,
Benoit Etienne
Publication year - 2019
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.5155
Subject(s) - rodenticide , warfarin , biology , computational biology , microbiology and biotechnology , toxicology , medicine , cardiology , atrial fibrillation
Second generation anticoagulant rodenticides (SGAR) are generally highly efficient for rodent management even towards warfarin‐resistant rodents. Nevertheless, because of their long tissue‐persistence, they are very associated with non‐target exposure of wildlife and have been identified as ‘Candidates for Substitution’ by the European Union's competent authority. A promising way to reduce ecotoxicity issues associated to SGAR could be the improvement of SGAR based on their stereoisomery, and due to this improvement, positioning about SGAR might be reconsidered. © 2018 Society of Chemical Industry