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The use of substituted alkynyl phenoxy derivatives of piperonyl butoxide to control insecticide‐resistant pests
Author(s) -
Philippou Despina,
Borzatta Valerio,
Capparella Elisa,
Moroni Leni,
Field Linda,
Moores Graham
Publication year - 2016
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.4234
Subject(s) - piperonyl butoxide , imidacloprid , myzus persicae , pyrethroid , chemistry , in vivo , pest analysis , toxicology , insecticide resistance , pesticide , biology , organic chemistry , toxicity , microbiology and biotechnology , agronomy , botany , aphid
BACKGROUND Derivatives of piperonyl butoxide with alkynyl side chains were tested in vitro and in vivo against pyrethroid‐resistant Meligethes aeneus and imidacloprid‐resistant Myzus persicae . RESULTS Synergists with the alkynyl side chain were more effective inhibitors of P450 activity in vitro than piperonyl butoxide, and demonstrated high levels of synergism in vivo , with up to 290‐fold synergism of imidacloprid against imidacloprid‐resistant M. persicae . CONCLUSIONS These ‘second‐generation’ synergists could overcome metabolic resistance in many pest species and possibly enable reduced rates of insecticide application in some cases. © 2016 Society of Chemical Industry