The use of substituted alkynyl phenoxy derivatives of piperonyl butoxide to control insecticide‐resistant pests | Zendy

Philippou Despina | Zendy; Borzatta Valerio | Zendy; Capparella Elisa | Zendy; Moroni Leni | Zendy; Field Linda | Zendy; Moores Graham | Zendy

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The use of substituted alkynyl phenoxy derivatives of piperonyl butoxide to control insecticide‐resistant pests

Author(s) -

Philippou Despina,

Borzatta Valerio,

Capparella Elisa,

Moroni Leni,

Field Linda,

Moores Graham

Publication year - 2016

Publication title -

pest management science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.296

H-Index - 125

eISSN - 1526-4998

pISSN - 1526-498X

DOI - 10.1002/ps.4234

Subject(s) - piperonyl butoxide , imidacloprid , myzus persicae , pyrethroid , chemistry , in vivo , pest analysis , toxicology , insecticide resistance , pesticide , biology , organic chemistry , toxicity , microbiology and biotechnology , agronomy , botany , aphid

BACKGROUND Derivatives of piperonyl butoxide with alkynyl side chains were tested in vitro and in vivo against pyrethroid‐resistant Meligethes aeneus and imidacloprid‐resistant Myzus persicae . RESULTS Synergists with the alkynyl side chain were more effective inhibitors of P450 activity in vitro than piperonyl butoxide, and demonstrated high levels of synergism in vivo , with up to 290‐fold synergism of imidacloprid against imidacloprid‐resistant M. persicae . CONCLUSIONS These ‘second‐generation’ synergists could overcome metabolic resistance in many pest species and possibly enable reduced rates of insecticide application in some cases. © 2016 Society of Chemical Industry

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