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Quercetin interacts with Cry1Ac protein to affect larval growth and survival of Helicoverpa armigera
Author(s) -
Li Zhen,
Guan Xiumin,
Michaud J P,
Zhang Qingwen,
Liu Xiaoxia
Publication year - 2016
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.4160
Subject(s) - cry1ac , helicoverpa armigera , pest analysis , quercetin , biology , bt cotton , pesticide , toxicity , larva , toxicology , microbiology and biotechnology , genetically modified crops , botany , agronomy , transgene , chemistry , biochemistry , antioxidant , organic chemistry , gene
BACKGROUND Bt cotton has been widely planted in China for over a decade to control H. armigera , but field surveys indicate increasing resistance in the pest. It has been speculated that accumulating plant secondary compounds in mature cotton may interact with Bt toxins and affect the toxicity of Bt to H. armigera . RESULTS Both quercetin, one of the main flavonoids in cotton, and the Bt toxin Cry1Ac protein had significant negative effects on the growth, development and survival of H. armigera when added singly to artificial diet, but their effects were inhibited when added in combination. Quercetin was antagonistic to Cry1Ac toxicity at all tested concentrations. CONCLUSION The accumulation of quercetin might be one factor contributing to the reduced toxicity of mature Bt cotton plants to H. armigera , and could partially explain the reduced efficacy of Cry1Ac in controlling this pest in the field. © 2015 Society of Chemical Industry