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Effect of pyrethroids on carbohydrate metabolic pathways in common carp, Cyprinus carpio
Author(s) -
Kamalaveni K,
Gopal V,
Sampson Ursula,
Aruna D
Publication year - 2001
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.395
Subject(s) - pentose phosphate pathway , fenvalerate , deltamethrin , cyprinus , biology , common carp , cypermethrin , carbohydrate metabolism , biochemistry , dehydrogenase , carbohydrate , chemistry , toxicology , metabolism , enzyme , pesticide , glycolysis , fishery , fish <actinopterygii> , agronomy
The activity levels of succinate dehydrogenase (SDH) and glucose‐6‐phosphate dehydrogenase (G6PD) were assessed in various tissues of Cyprinus carpio var communis which had been exposed to lethal concentrations of group‐II pyrethroids (deltamethrin, cypermethrin, fenvalerate and fluvalinate) for a period of 72 h. The results indicated a steady decrease in SDH activity with a concomitant increase in G6PD activity. The decreased SDH activity indicated inhibition of SDH at mitochondrial level and the increased G6PD activity an enhancement of an alternative pathway of carbohydrate metabolism, viz the hexose monophosphate shunt (HMP) or pentose phosphate pathway as a biochemical adaptation to overcome the toxic stress. © 2001 Society of Chemical Industry