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Acaricidal activities of β ‐caryophyllene oxide and structural analogues derived from Psidium cattleianum oil against house dust mites
Author(s) -
Oh MinSeok,
Yang JiYeon,
Kim MinGi,
Lee HoiSeon
Publication year - 2014
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.3608
Subject(s) - benzyl benzoate , caryophyllene , psidium , chemistry , organic chemistry , chromatography , essential oil , botany , biology
BACKGROUND This study was to evaluate the acaricidal activities of an active compound isolated from Psidium cattleianum and structural analogues against Dermatophagoides farinae and D. pteronyssinus . β ‐Caryophyllene oxide was isolated using chromatographic techniques . RESULTS Based on the 50% lethal concentration ( LD 50 ) values against D. farinae using the fumigant method, β ‐caryophyllene oxide (1.36 µg cm −2 ) was ∼ 7.52 times more toxic than benzyl benzoate (10.23 µg cm −2 ), followed by α ‐caryophyllene (1.75 µg cm −2 ) and β ‐caryophyllene (3.13 µg cm −2 ). Against D. pteronyssinus , β ‐caryophyllene oxide (1.38 µg cm −2 ) was ∼ 7.22 times more toxic than benzyl benzoate (9.96 µg cm −2 ), followed by α ‐caryophyllene (1.71 µg cm −2 ) and β ‐caryophyllene (3.58 µg cm −2 ). In the contact toxicity method against D. farinae , β ‐caryophyllene oxide (0.44 µg cm −2 ) was ∼ 17.27 times more active than benzyl benzoate (7.60 µg cm −2 ), followed by α ‐caryophyllene (0.67 µg cm −2 ) and β ‐caryophyllene (0.91 µg cm −2 ). Against D. pteronyssinus , β ‐caryophyllene oxide (0.47 µg cm −2 ) was ∼ 13.06 times more effective than benzyl benzoate (6.14 µg cm −2 ), followed by α ‐caryophyllene (1.71 µg cm −2 ) and β ‐caryophyllene (3.58 µg cm −2 ) . CONCLUSION β ‐Caryophyllene oxide and structural analogues have potential for development as preventive agents for the control of house dust mites. © 2013 Society of Chemical Industry