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Synthesis and antifeedant activity of novel alpha‐asarone derivatives against stored‐product pests
Author(s) -
Łozowicka Bożena,
Kaczyński Piotr
Publication year - 2013
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.3461
Subject(s) - sitophilus , trogoderma granarium , natural product , alpha (finance) , stereochemistry , broad spectrum , chemistry , carbon 13 nmr , pyrethrum , organic chemistry , biology , toxicology , pest analysis , botany , combinatorial chemistry , pesticide , agronomy , medicine , construct validity , nursing , patient satisfaction
Background Alpha‐asarone (2,4,5‐trimethoxypropenylbenzene) derivatives represent a new series of compounds that possess good antifeedant activity against different stored‐product pests.Results A total of 23 novel alpha‐asarone derivatives were synthesised and identified by 1 H NMR , 13 C NMR and IR , and their feeding deterrent activities were tested against Sitophilus granarius L., Trogoderma granarium Ev. and Tribolium confusum Duv. Ten compounds showed strong antifeedant activities.Conclusion Some of the title compounds displayed very good and broad‐spectrum activities against adult and larval Coleoptera. The results indicate that the presence of a double bond in the side chain and three methoxy groups is important for antifeedant activity. © 2012 Society of Chemical Industry