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The action of herbicides on fatty acid biosynthesis and elongation in barley and cucumber
Author(s) -
Yang Xueying,
Guschina Irina A,
Hurst Samantha,
Wood Sophie,
Langford Mike,
Hawkes Tim,
Harwood John L
Publication year - 2010
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.1944
Subject(s) - fatty acid synthesis , acetyl coa carboxylase , fatty acid , hordeum vulgare , biochemistry , biology , lipid metabolism , herbicide resistance , mode of action , biosynthesis , pyruvate carboxylase , poaceae , botany , gene , enzyme
BACKGROUND: Herbicides that affect lipid metabolism have been used commercially for many years. Here, napropamide, diphenamid, dimethachlor and cafenstrole are compared; these have all been classified by the Herbicide Resistance Action Committee (HRAC) as K 3 herbicides and inhibitors of cell division and/or synthesis of very‐long‐chain fatty acids (VLCFAs). In addition, spiro‐decanedione A and pinoxaden dione are compared as inhibitors of lipid synthesis through inhibition of acetyl‐CoA carboxylase (ACCase). RESULTS: Whereas the chloracetamide dimethachlor and the carboxyamide cafenstrole potently inhibited VLCFA synthesis in both barley and cucumber, the acetamides napropamide and diphenamid which are also classified as K 3 herbicides and likewise the unclassified herbicide cinmethylin did not. The graminicide pinoxaden dione inhibited de novo fatty acid synthesis in barley, but not in cucumber, and correspondingly inhibited the plastid form of maize ACCase much more than the cytosolic form (IC 50 values of 0.1 and 17 µ M ). By contrast, spiro‐decanedione A exhibited herbicidal effects not only on grasses but also on broad leaves, strongly inhibited maize cytosolic ACCase and inhibited synthesis of VLCFAs in cucumber. CONCLUSIONS: The acetamides napropamide and diphenamid, which do not inhibit VLCFA synthesis, should be classified separately from K 3 herbicides that do. Pinoxaden dione and spiro‐decanedione A represent new classes of chemicals acting on plant lipid synthesis. Copyright © 2010 Society of Chemical Industry