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Synthesis and bioactivity of some new N ‐aryl/alkyl/cyclohexyl‐ N ′‐(2,3‐dihydro‐2‐oxo‐4 H ‐benz[ e ][1,3,2]oxazaphosphorin‐2‐yl) ureas
Author(s) -
Kiran YB,
Gunasekar D,
Devendranath Reddy C,
Suresh Reddy C,
Tran Kevin,
Le Thanh,
Darrell Berlin K,
Srinivasan S,
Charitha Devi M
Publication year - 2005
Publication title -
pest management science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.296
H-Index - 125
eISSN - 1526-4998
pISSN - 1526-498X
DOI - 10.1002/ps.1067
Subject(s) - antimicrobial , triethylamine , aryl , chemistry , alkyl , bacteria , rhizobium , fusarium oxysporum , medicinal chemistry , urea , stereochemistry , organic chemistry , biology , biochemistry , botany , genetics , gene
Several new substituted oxazaphosphorinyl urea derivatives of the type RR′P(O)NHC(O)NHR″ were synthesized from α‐(3‐chloro‐4‐fluoroanilino)‐ o ‐cresol by reaction with chlorides of aryl/alkyl/cyclohexyl carbamidophosphoric acids in the presence of triethylamine at 0–50 °C. Their significant insecticidal and antimicrobial activity and promotion of Rhizobium bacteria growth in the soil without effect on the host tissue suggests their possible commercial application as ecofriendly pesticides and antimicrobial agents. Copyright © 2005 Society of Chemical Industry