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Computer modeling of a potential agent against SARS‐Cov ‐2 ( COVID ‐19) protease
Author(s) -
Lesk Arthur M.,
Konagurthu Arun S.,
Allison Lloyd,
Garcia de la Banda Maria,
Stuckey Peter J.,
Abramson David
Publication year - 2020
Publication title -
proteins: structure, function, and bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.699
H-Index - 191
eISSN - 1097-0134
pISSN - 0887-3585
DOI - 10.1002/prot.25980
Subject(s) - covid-19 , protease , virology , chemistry , biology , enzyme , medicine , biochemistry , infectious disease (medical specialty) , disease , pathology , outbreak
We have modeled modifications of a known ligand to the SARS‐CoV‐2 (COVID‐19) protease, that can form a covalent adduct, plus additional ligand‐protein hydrogen bonds.