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Rigidity loss of protein macromolecule induced by force—Effective field theory
Author(s) -
Meilikhov E.Z.,
Farzetdinova R.M.
Publication year - 2014
Publication title -
proteins: structure, function, and bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.699
H-Index - 191
eISSN - 1097-0134
pISSN - 0887-3585
DOI - 10.1002/prot.24471
Subject(s) - rigidity (electromagnetism) , macromolecule , force field (fiction) , field (mathematics) , materials science , biophysics , chemistry , physics , composite material , mathematics , biology , quantum mechanics , biochemistry , pure mathematics
In the framework of the effective field theory for the order parameter, which characterizes the degree of deviating the protein globule structure from its native state, the phase transition of the protein macromolecule from the elastic state into the plastic one under its mechanical stretching is considered. Elastic properties of a protein are studied as a function of the applied force, temperature, and the mean coordination number of the protein “network.” Proteins 2014; 82:966–974. © 2013 Wiley Periodicals, Inc.