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Assessment of intramolecular contact predictions for CASP7
Author(s) -
Izarzugaza José M. G.,
Graña Osvaldo,
Tress Michael L.,
Valencia Alfonso,
Clarke Neil D.
Publication year - 2007
Publication title -
proteins: structure, function, and bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.699
H-Index - 191
eISSN - 1097-0134
pISSN - 0887-3585
DOI - 10.1002/prot.21637
Subject(s) - intramolecular force , computer science , artificial intelligence , machine learning , chemistry , stereochemistry
Predictions of intramolecular residue–residue contacts were assessed as part of the seventh community‐wide Critical Assessment of Structure Prediction experiment (CASP7). As in past assessments, we focused on contacts that lie far apart in sequence as these are likely to be more informative in predicting protein structure. One lab did somewhat better than others according to our assessment, and there is some reason to think that this lab's results represent progress over CASP6. In general, contacts inferred from 3D structural predictions are similar in accuracy to those predicted by contact prediction methods. However, contact prediction methods were more accurate for some targets. Proteins 2007. © 2007 Wiley‐Liss, Inc.